Abstract: Published scientific papers included in China National Knowledge Infrastructure (CNKI) and the core collection of Web of Science (WoS) of Center for Agricultural Resources Research, Institute of Genetics and Developmental Biology, Chinese academy of Sciences (CARR) since 1978, when CARR was launched, were bibliometrically analyzed to reveal the changes in research hotspots and trends of CARR since its' establishment. The CNKI and WoS searching results showed 2 052 papers of researches conducted by CARR since 1978, of which 1 467 papers were in Chinese and included in CNKI, and 585 papers were in English and included in WoS. Annual published Chinese papers number increased and peaked in 2005, and then kept at around 50 though slightly decreased. Papers in English were mainly published after 2002 and increased quickly with annual increase rate of 26.85% from 2003 to 2017. There were 118 papers in Chinese and 44 papers in English cited more than 50 in CNKI and WoS, respectively. And Chinese papers were published in 235 journals, and English papers in 237 journals. The average impact factors of the Chinese journals and English journals publishing top 10 papers were 1.022 and 3.411, respectively. The papers were mainly supported by the Program of Knowledge Innovation of Chinese Academy of Sciences, National Natural Science Foundation of China, National Basic Research Program of China (973 Program), National High-tech R&D Program of China (863 Program) and National Key Technologies R&D Program of China. The international cooperation of CARR increased yearly, and there were 73 international cooperation funds supporting the researches of CARR, such as International Cooperation Project of Chinese Academy of Sciences, Fund of Australia International Agricultural Research Center, National Study Abroad Fund of China, European Community Fund. The institutions collaborating with CARR to publish scientific papers were mainly from Hebei Province, Beijing City, Shandong Province and Shanxi Province, while the international institutions were mainly from USA, Japan, Netherland, Australia, Denmark, Pakistan. Co-occurrence analysis of keywords of published papers based on CiteSpace showed that the keywords in the first ten years since CARR establishment were less with weak interconnection. After that, the research keywords increased and peaked around 2000. The interconnections among keywords were increasingly close. The studied crops were wheat and maize, the areas concentrated in the North China Plain. Under the climate change background, the research works of CARR now are mainly focusing on crop cultivation, breeding and molecular biology; water resources and water-saving agriculture; carbon and nitrogen recycle of agroecosystem; reclamation of salt soil land, and utilization of halophyte and salt water resources. In summary, CARR have formed its' special research area and made remarkable research achievements.