Abstract: The implementation of rural revitalization strategy has provided sufficient policy guarantee for rural infrastructure construction, rural economic structure innovation and rural technical personnel training; in turn greatly improving the external environment and internal requirements of rural e-commerce development. Also the development of rural e-commerce has promoted the implementation of rural revitalization strategy in terms of market expansion, industrial upgrading and financing. In order to achieve high-efficiency interaction between the two strategies, we constructed a system dynamics model of interactive development between rural e-commerce and rural revitalization to show causal relationship and dynamic feedback mechanism among the four subsystems of number of rural e-commerce operators, agricultural special product market, rural e-commerce professional talents scale and capital scale. Based on statistical data of rural economic development in China for 2010-2016, we simulated the interaction between rural e-commerce and rural revitalization. Stability and validity tests of the system dynamics model showed that the model truly reflected actual system structure and function of rural e-commerce and rural revitalization in rural economic growth. On this basis, the policy of the interactive development between rural e-commerce and rural revitalization was further simulated by adjusting the values of four policy variables of rural e-commerce fixed asset investment parameter, rural e-commerce education investment parameter, agricultural financial subsidy factor and rural resident consumption subsidy factor. The simulation results showed that the main factor influencing interactive development between rural e-commerce and rural revitalization was the intensity of agricultural financial subsidies. Also relevant supporting policies had different effects on the process of interactive development between rural e-commerce and rural revitalization, with obvious stage characteristics. Therefore, gradually increasing the intensity of agricultural financial subsidies and building comprehensive policy support systems were necessary to realize interactive development between rural e-commerce and rural revitalization. Also according to current conditions of rural e-commerce development and rural revitalization strategy implementation, there was need to focus on promoting relevant policies to promote interactive development between rural e-commerce and rural revitalization in a phased and targeted manner.