Abstract: Drought affects plant growth most seriously. Molecular response and signal transduction are induced in water stress. Water-stress inducible gene expresses some important function protein and regulatory protein to protect plant cell from injury. The identified protein includes transmembrane channel protein,water regulator,transportor or synthetase,lea protein,antioxidant enzyme,water-stress protein,regulatory protein, etc.At least four independent signal transduction pathways exist among water-stress inducible gene expression. Plant cell percepts water stress by turger or receptor,than transforms extracellular signal to intracellular signal,and induces second messengers. Among the primary signal cascades,two pathways are ABA dependent and two ABA independent,some cis-acting elements and transcription factor are identified by gene expression and regulation