Abstract: Ecological safety of the dry-hot valley of Jinsha River is closely related with the industrial and agricultural sustainable development in the middle-lower reaches of Yangtze River and Jinsha River basin in west development of China．Present situation of ecological safety in Yuanmou dry-hot valley of Jinsha River is investigated in this work It is shown that adverse natural condition，serious vegetation degradation and forest loss，harmful cultivation and overgrazing，weak ecological consciousness，low productive forces and backward economy are the main reasons to threaten the regional ecosafety．Finally，fundamental Ineasures on establishing the eco-safety system of the dry-hot valley of Jinsha River are put forward.