Abstract: Using the orthogonal quadratic regression design method，a cultivation technology mode to retain maize high yield with applying fertilizer in extractive quantity is found out，by which nonpoint-source pollution can be controlled．From the research result，a numeric rllode of the density of maize planting，quantity of applying N and quantity of applying P is built，and the applying technologies of fertilizer are defined including deep hole-application of P fertilizer and deep application of N fertilizer for the rapid growth of its ears．